Dr. Amin Majdalawieh | American University of Sharjah
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Profile

College / Department

College of Arts and Sciences
Department of Biology, Chemistry and Environmental Sciences

Teaching areas

Biochemistry, Genetics, Immunology, Cell &amp; Molecular Biology, Cell Signaling, General Biology, Human Anatomy &amp; Physiology, Human Biology

Research areas

My research interests are diverse and inter-disciplinary, but I am mostly interested in studying the immunomodulatory and anti-cancer properties of various natural products, spices, herbs and other food additives. I am also interested in understanding the molecular mechanisms that link macrophage-driven inflammation to conditions such as heart disease (atherosclerosis), obesity, and cancer. So, my research interests revolve around metabolic syndrome, immunology, and medicinal chemistry.

Education

PhD, Biochemistry &amp; Molecular Biology, Dalhousie University, Canada, 2006
MS, Microbiology &amp; Immunology, McGill University, Canada, 2003
BS, Microbiology &amp; Immunology and biology, Dalhousie University, Canada, 2000

Professional experience

Professor, Department Of Biology, Chemistry &amp; Environmental Sciences, American University of Sharjah, Sharjah, United Arab Emirates, 2017 - Present
Associate Professor,, Department Of Biology, Chemistry &amp; Environmental Sciences, American University of Sharjah, Sharjah, United Arab Emirates, 2011 - 2017
Assistant Professor, Department Of Biology, Chemistry &amp; Environmental Sciences, American University of Sharjah, Sharjah, United Arab Emirates, 2007 - 2011
Visiting Associate, Department Of Biochemistry &amp; Molecular Biology, Dalhousie University, Nova Scotia, Canada, 2010 - 2010
Post-doctoral Fellow, Department Of Biochemistry &amp; Molecular Biology, Dalhousie University, Nova Scotia, Canada, 2006 - 2007
Laboratory Instructor, Department Of Biochemistry &amp; Molecular Biology, Dalhousie University, Nova Scotia, Canada, 2006 - 2006
Laboratory Instructor, Department Of Biology, Saint Mary's University, Nova Scotia, Canada, 2006 - 2006
Laboratory Instructor, Department Of Biochemistry &amp; Molecular Biology, Dalhousie University, Nova Scotia, Canada, 2006 - 2006
Teaching Assistant, Department Of Biochemistry &amp; Molecular Biology, Dalhousie University, Nova Scotia, Canada, 2003 - 2006
Teaching Assistant, Department Of Biology And Department Of Microbiology &amp; Immunology, McGill University, Quebec, Canada, 2002 - 2002
Teaching Assistant, Department Of Biology, Saint Mary's University, Nova Scotia, Canada, 1998 - 1999

Contact

[email protected]
+971 6 515 2429

Dr. Amin Majdalawieh

Professor
PhD, Dalhousie University, Canada

Amin Majdalawieh served as an instructor at several universities in Halifax, Canada and pursued a post-doctoral fellowship in the Department of Biochemistry and Molecular Biology at Dalhousie University. His teaching interests are in biochemistry, genetics, immunology, cell and molecular biology, cell signaling, general biology, human anatomy and physiology. He received several research awards. His main research interests include cardiovascular disease (atherosclerosis), cancer, obesity, signal transduction, inflammation, nutritional immunology, natural products, and medicinal chemistry.

Publications

Samar Shurbaji, Faleh Al Tamimi, Mahmoud Al Ghwairi, Dayana El Chaar, Salma Younes, Amin Majdalawieh, Gianfranco Pintu, Nader Al-dewik And Gheyath Nasrallah. High-sensitive detection and quantitation of thyroid-stimulating hormone (TSH) from capillary/fingerstick and venepuncture whole-blood using fluorescence-based rapid lateral flow Immunoassay (LFIA), Heliyon
Amin Majdalawieh, Sogand Ahari, Sarah Yousef And Gheyath Nasrallah. Sesamol: a lignan in sesame seeds with potent anti-inflammatory and immunomodulatory properties, European Journal Of Pharmacolgy
Amin Majdalawieh, Aaram Eltayeb, Imad Abu-yousef And Sarah Yousef. The hypolipidemic and anti-atherogenic effects of sesamol and possible mechanisms of action, Molecules, 19 April (2nd Quarter/Spring) 2023
Fatema Hersi, Anusha Sebastian, Hamadeh Tarazi, Vunnam Srinivasulu, Ahmed Mostafa, Abdou Allayeh, Cong Zeng, Ibrahim Hachim, Shan-lu Liu, Imad Abu-yousef, Amin Majdalawieh, Dana Zaher, Hany Omar And Taleb Al-tel. Discovery of novel papain-like protease inhibitors for potential treatment of COVID-19, European Journal Of Medicinal Chemistry, 17 April (2nd Quarter/Spring) 2023
Nadin Younes, Mahmoud Al Ghwairi, Sahar Da’as, Eiman Al Zaabi, Amin Majdalawieh, Nader Al-dewik And Gheyath Nasrallah. Performance evaluation of a new fluorescent-based lateral flow immunoassay for quantification of HbA1c in diabetic patients, Frontiers In Bioscience – Landmark, 23 March 2023
Gourishetty Srikanth, Anil Ravi, Anusha Sebastian, Jobi Joseph, Monther Khanfar, Mohammed El-gamal, Raed Al-qawasmeh, Imad Abu-yousef, Amin Majdalawieh And Taleb Al-tel. Diastereoselective synthesis of camptothecin-like scaffolds: construction of a new class of pseudo-natural products, European Journal Of Organic Chemistry, 12 February 2023
Gourishetty Srikanth, Anil Ravi, Anusha Sebastian, Jobi Joseph, Monther Khanfar, Mohammed El-gamal, Raed Al-qawasmeh, Imad Abu-yousef, Amin Majdalawieh And Taleb Al-tel. Stereodivergent transformation of azepino[3,4,5-cd]indoles en route to nature-inspired scaffolds, European Journal Of Organic Chemistry, 25 January (1st Quarter/Winter) 2023
Gourishetty Srikanth, Anil Ravi, Anusha Sebastian, Monther Khanfar, Imad Abu-yousef, Amin Majdalawieh, Mohammed El-gamal, Bilal Alkubaisi, Afnan Shahin, Jobi Joseph And Taleb Al-tel. Stereodivergent desymmetrization of phenols en route to modular access to densely functionalized quinazoline and oxazine scaffolds, Journal Of Organic Chemistry, 13 January (1st Quarter/Winter) 2023
Harsh Kumar, Reena Singh, Daljeet Dhanjal, Chirag Chopra, Natália Cruz-martins, Gheyath Nasrallah, Amin Majdalawieh, Sivakumar Manickam, Shahida Siddiqui, Dinesh Kumar, Indu Sharma And Varun Sharma. Impact of phytoconstituents on oral health practices: a post COVID-19 observation, Food Science And Health Wellness
Nadin Younes, Duaa Al-sadeq, Farah Shurrab, Hadeel Zedan, Haissam Abou-saleh, Bushra Abo-halawa, Fatima Alhamaydeh, Amira Elsharafi, Hanin Daas, Swapna Thomas, Sahar Aboalmaaly, Afra Al Farsi, Reeham Al-buainain, Samar Ataelmannan, Jiji Paul, Amana Al Saadi, Hadi Yassine, Amin Majdalawieh, Ahmed Ismail, Laith Abu-raddad And Gheyath Nasrallah. Validation of a novel fluorescent lateral flow assay for rapid qualitative and quantitative assessment of total anti-SARS-CoV-2 S-RBD binding antibody units (BAU) from plasma or fingerstick whole-blood of COVID-19 vaccinees, Vaccines, 15 August 2022
Amin Majdalawieh, Sarah Yousef, Imad Abu-yousef And Gheyath Nasrallah. Immunomodulatory and anti-inflammatory effects of sesamin: mechanisms of action and future directions, Critical Reviews In Food Science And Nutrition, 30 June 2022
Vunnam Srinivasulu, Gourishetty Srikanth, Monther Khanfar, Imad Abu-yousef, Amin Majdalawieh, Ralph Mazitschek, Subbaiah Setty, Anusha Sebastian And Taleb Al-tel. Stereodivergent complexity-to-diversity strategy en route to the synthesis of nature-inspired skeleta, Journal Of Organic Chemistry, 11 June 2022
Amin Majdalawieh, Sarah Yousef, Imad Abu-yousef And Gheyath Nasrallah. Immunomodulatory and anti-inflammatory effects of berberine in lung tissue and its potential application in prophylaxis and treatment of COVID-19, Frontiers In Bioscience – Landmark, 20 May 2022
Nadin Younes, Alsahan, Asmaa Almesaifri, Sahar Da'as, Gianfranco Pintus, Amin Majdalawieh And Gheyath Nasrallah. JC-10 probe as a novel method for analyzing the mitochondrial membrane potential and cell stress in whole zebrafish embryos, Toxicology Research, 21 December 2021
Amin Majdalawieh, Sarah Yousef And Imad Abu-yousef. Potential immunomodulatory role of sesamin in combating immune dysregulation associated with COVID-19, Asian Pacific Journal Of Tropical Biomedicine, 30 September 2021
Vunnam Srinivasulu, Scott Sieburth, Monther Khanfar, Imad Abu-yousef, Amin Majdalawieh, Mani Ramanathan, Anusha Sebastian And Taleb Al-tel. Stereoselective late-stage transformations of indolo[2,3-a]quinolizines skeleta to nature-inspired scaffolds, Journal Of Organic Chemistry, 3 September 2021
Amin Majdalawieh, Sarah Yousef And Imad Abu-yousef. Thymoquinone, a major constituent in Nigella sativa seeds, is a potential preventative and treatment option for atherosclerosis, European Journal Of Pharmacology, 12 August 2021
Sarah Dalibalta, Amin Majdalawieh, Sarah Yousef, Mohammed Gusbi, Jason Wilson, Mark Tully And Gareth Davison. Objectively quantified physical activity and sedentary behavior in a young UAE population, Bmj Open Sport &amp; Exercise Medicine, 7 January (1st Quarter/Winter) 2021
Paul Schilf, Vunnam Srinivasulu, Maria Bolognesi, Saleh Ibrahim, Amin Majdalawieh, Imad Abu-yousef, Hany Omar, Raafat Elawady And Taleb Al-tel. Design and synthesis of nature-inspired chromenopyrroles as potential modulators of mitochondrial metabolism, Medicinal Chemistry Research, 30 November 2020
Maha Al-asmakh, Amin Majdalawieh, Aboubakr Abdullah, Nadin Younes, Sahar Da'as, A. Bahgat Radwan, Mostafa Sliem, Houria Ech-cherif, Gianfranco Pintus And Gheyath Nasrallah. AEO-7 surfactant is “super toxic” and induces severe cardiac, liver and locomotion damage in zebrafish embryos, Environmental Sciences Europe, 11 November 2020
Taleb Al-tel, Vunnam Srinivasulu, Mani Ramanathan, Nelson Soares, Anusha Sebastian, Maria Bolognesi, Imad Abu-yousef And Amin Majdalawieh. Stereocontrolled transformations of cyclohexadienone derivatives to access stereochemically rich and natural product-inspired architectures, Organic &amp; Biomolecular Chemistry, 18 September 2020
Sarah Dalibalta, Amin Majdalawieh And Herak Manjikian. Health benefits of sesamin on cardiovascular disease and its associated risk factors, Saudi Pharmaceutical Journal, 1 September 2020
Amin Majdalawieh, Sarah Dalibalta And Sarah Yousef. Effects of sesamin on fatty acid and cholesterol metabolism, macrophage cholesterol homeostasis and serum lipid profile: A comprehensive review, European Journal Of Pharmacology, 1 August 2020
Vunnam Srinivasulu, Paul Schilf, Saleh Ibrahim, Ihsan Shehadi, Omar Malik, Scott Sieburth, Monther Khanfar, Mohamad Hamad, Imad Abu-yousef, Amin Majdalawieh And Taleb Al-tel. Divergent strategy for diastereocontrolled synthesis of small- and medium-ring architectures, Journal Of Organic Chemistry, 29 July (3rd Quarter/Summer) 2020
Ola Al-jamal, Hadeel Al-jighefee, Nadin Younes, Roba Abdin, Maha Al-asmakh, A. Bahgat Radwan, Mostafa Sliem, Amin Majdalawieh, Gianfranco Pintus, Hadi Yassine, Aboubakr Abdullah, Sahar Da'as And Gheyath Nasrallah. Organ-specific toxicity evaluation of stearamidopropyl dimethylamine (SAPDMA) surfactant using zebrafish embryos, Science Of The Total Environment, 23 June 2020
Amin Majdalawieh, Jenna Farraj And Ronald Carr. Sesamum indicum (sesame) enhances NK anti-cancer activity, modulates Th1/Th2 balance, and suppresses macrophage inflammatory response, Asian Pacific Journal Of Tropical Biomedicine, 3 June 2020
Amin Majdalawieh, Mariam Massri And Hyo-sung Ro. AEBP1 is a novel oncogene: mechanisms of action and signaling pathways, Journal Of Oncology, 27 May 2020
N. Alsawaftah, A. Farooq, Salam Dhou And Amin Majdalawieh. Bioluminescence Imaging Applications in Cancer: A Comprehensive Review, Ieee Reviews In Biomedical Engineering, 15 May 2020
Prince Das, Amin Majdalawieh, Imad Abu-yousef, Srinivasan Narasimhan And Palmiro Poltronieri. Use of a hydroalcoholic extract of Moringa oleifera leaves for the green synthesis of bismuth nanoparticles and evaluation of their anti-microbial and antioxidant activities, Materials, 15 February 2020
Prince Das, Imad Abu-yousef, Amin Majdalawieh, Srinivasan Narasimhan And Palmiro Poltronieri. Green synthesis of encapsulated copper nanoparticles using a hydroalcoholic extract of Moringa oleifera leaves and assessment of their antioxidant and anti-microbial activities, Molecules
C Gunasekar, Imad Abu-yousef, S Narasimhan And Amin Majdalawieh. Analysis of Macro and Micro Elemental Composition of Different Extracts and Finished Products of the Medicinal Herb - Terminalia Bellirica, Mediterranean Journal Of Chemistry, 17 July (3rd Quarter/Summer) 2019
Conjeevaram Gunasekar, Imad Abu-yousef, Amin Majdalawieh And Srinivasan Narasimhan. Pharmacognostic evaluation of Terminalia chebula standard extracts and finished products, Mediterranean Journal Of Chemistry, 17 July (3rd Quarter/Summer) 2019
Amin Majdalawieh And Zeenah Mansour. Sesamol, a major lignan in sesame seeds (Sesamum indicum): anti-cancer properties and mechanisms of action, European Journal Of Pharmacology, 1 May 2019
Amin Majdalawieh. The role of adipocyte enhancer-binding protein-1 in atherosclerosis, other cardiovascular diseases, and cardioembolic stroke, 1 October (4th Quarter/Autumn) 2018
Amin Majdalawieh, Marsha Kanan, Oussama El-kadri And Sofian Kanan. Recent advances in gold and silver nanoparticles: synthesis and applications, Journal Of Nanoscience And Nanotechnology, 2014

Conference Presentations

A MATHEMATICAL MODELING APPROACH FOR ELUCIDATING THE SIGNALING PATHWAYS INVOLVED IN MACROPHAGE CHOLESTEROL HOMEOSTASIS AND VALIDATION OF AEBP1 ROLE IN ATHEROSCLEROSIS, The 90th European Atherosclerosis Society Congress (eas Congress), 23 May 2022
A mathematical modeling approach for elucidating the signaling pathways involved in macrophage cholesterol homeostasis and validation of AEBP1 role in atherosclerosis, 90th European Atherosclerosis Society Congress – Eas 2022, Milan, Italy, 22 May 2022
Anti-bacterial and anti-fungal activity of xanthones obtained via semi-synthetic modification of α-mangostin from Garcinia mangostana, 2nd World Congress On Chemistry 2019, Rome, Italy, October 2019
The role of adipocyte enhancer-binding protein-1 in atherosclerosis, other cardiovascular diseases, and cardioembolic stroke, 15th Annual Conference Of The Esc Working Group On Myocardial &amp; Pericardial Diseases, October 2018

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